Searchable abstracts of presentations at key conferences in endocrinology

ea0016p199 | Diabetes and cardiovascular diseases | ECE2008

24 h glycemia variability correlates with arterial structure alteration in type 1 diabetes

Colombo Manuela Carla , Gamba Pierluigi , Failla Monica , Paleari Felice , Rigoldi Mauro , Perego Rita , Giannattasio Cristina , Mancia Giuseppe

Objective: Diabetes mellitus is characterized by vascular complications associated with arterial thickening. Although strict glycaemic control is clinically beneficial, limited or no evidence exists as to whether arterial damage is positively related to blood glucose levels and variability.Methods: Study purpose was to asses the relationship between arterial thickness and 24 h mean and S.D. of blood glucose in type 1 diabetes. Fifteen type...

ea0016p519 | Obesity | ECE2008

In the metabolic syndrome adrenergic overdrive is independent on the obese state

Colombo Manuela Carla , Quarti-Trevano Fosca , Dell'Oro Raffaella , Gamba Pierluigi , Arenare Francesca , Perego Rita , Ilardo Valeria , Grassi Guido , Mancia Giuseppe

Objective: The metabolic syndrome (MS) is characterized by a marked sympathetic activation. Whether this adrenergic overdrive is mainly dependent on the obese state or it can be detected also in absence of obesity is unknown, however.Design and Methods: In 25 male patients (age 41.4±yrs., mean±S.E.M.) with MS (ATP III criteria) and in 12 age-matched healthy male controls, we measured body mass index (BMI), waist circumference (WC...